Spravato Ketamine Nasal Spray

Description

If you’re an adult with major depressive disorder (MDD) and haven’t responded adequately to two or more oral antidepressants, adding SPRAVATO to your treatment plan might be beneficial. This is particularly relevant if you are experiencing treatment-resistant depression (TRD).

**What is Spravato?**
SPRAVATO is the sole FDA-approved nasal spray formulated specifically for TRD. It functions as an NMDA receptor antagonist, targeting a brain pathway that influences glutamate, which is thought to play a role in its mechanism of action. It’s important to note that the safety and efficacy of SPRAVATO in preventing suicide or reducing suicidal thoughts or actions have not been established. SPRAVATO is not a substitute for hospitalization if deemed necessary by a healthcare provider, regardless of any improvements seen after initial treatment.

For more information, visit: [SPRAVATO Official Website](https://www.spravato.com/what-is-spravato#what-makes-spravato-different)

**Administration of SPRAVATO:**
SPRAVATO is administered via a nasal spray under the supervision of a healthcare provider in a medical setting. Your provider will instruct you on the proper use of the nasal spray device. They will also determine your dosage and treatment schedule. It’s crucial to adhere to this schedule precisely as prescribed. Monitoring by a healthcare professional is required during and after administration to ensure safety before you leave the medical facility. Transportation arrangements should be made for someone to drive you home following treatment.

If a treatment session is missed, your healthcare provider may adjust your dosage and schedule. To minimize nausea and vomiting, avoid eating for at least 2 hours and drinking liquids for at least 30 minutes before administration. If you use nasal corticosteroids or decongestants, take them at least one hour before using SPRAVATO.

**Precautions While Taking SPRAVATO:**
Avoid driving, operating machinery, or performing tasks requiring full alertness after treatment. These activities should be avoided until the day after a restful sleep.

**Potential Side Effects of SPRAVATO:**
Serious side effects include increased blood pressure, which can last about four hours post-administration. Blood pressure will be monitored before and after treatment. Immediate attention is needed if symptoms like chest pain, shortness of breath, severe headaches, changes in vision, or seizures occur. Other concerns include cognitive impairment and bladder issues—report any difficulties with thinking, memory, or urination to your healthcare provider.

Common side effects when taken with an oral antidepressant may include feelings of disconnection, dizziness, nausea, sleepiness, vertigo, numbness, anxiety, lethargy, vomiting, euphoria, and sensations of being intoxicated.

It is essential to discuss all health issues with your healthcare provider to ensure SPRAVATO is safe and suitable for your specific condition.